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Web site : https://jfantini.jimdo.com
PUBLICATIONS :- 2023 - Azzaz F, Hilaire D, Fantini J.
Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors.
Chem Biol Interact, 373 : 110384 - 2023 - Azzaz F, Chahinian H, Yahi N, Fantini J, Di Scala C.
AmyP53 Prevents the Formation of Neurotoxic β-Amyloid Oligomers through an Unprecedent Mechanism of Interaction with Gangliosides: Insights for Alzheimer's Disease Therapy.
Int J Mol Sci, 24 : 1760 - 2022 - Azzaz F, Yahi N, Di Scala C, Chahinian H, Fantini J.
Ganglioside binding domains in proteins: Physiological and pathological mechanisms
Advances in Protein Chemistry and Structural Biology, 128 : 289-324 - 2022 - Azzaz F, Fantini J.
The epigenetic dimension of protein structure
Biomolecular Concepts, 13 : 55-60 - 2022 - Ramirez-Franco JJ, Azzaz F, Sangiardi M, Ferracci G, Youssouf F, Popooff MR, Seagar M, Lévêque C, Fantini JEl Far O.
Molecular landscape of BoNT/B bound to a membrane-inserted synaptotagmin/ganglioside complex
Cell Mol Life Sci, 79 : 496 - 2022 - Azzaz F, Hilaire D, Fantini J.
Structural Basis of Botulinum Toxin Type F Binding to Glycosylated Human SV2A: In Silico Studies at the Periphery of a Lipid Raft
Biomolecule, 12 : 1821 - 2022 - Di Scala C, Amstrong N, Chahinian H, Chabrière E, Fantini J, Yahi N.
AmyP53, a Therapeutic Peptide Candidate for the Treatment of Alzheimer's and Parkinson's Disease: Safety, Stability, Pharmacokinetics Parameters and Nose-to Brain Delivery
Int J Mol Sci, 23 : 13383 - 2021 - Fantini J, Chahinian H, Yahi N.
Leveraging coronavirus binding to gangliosides for innovative vaccine and therapeutic strategies against COVID-19
Biochemical and Biophysical Research Communication, 538 : 132-136 - 2021 - Fantini J, Yahi N, Azzaz F, Chahinian H.
Structural dynamics of SARS-CoV-2 variants: A health monitoring strategy for anticipating Covid-19 outbreaks
Journal of Infection, 83 : 197-206 - 2021 - Yahi N, Di Scala C, Chahinian H, Fantini J.
Innovative treatment targeting gangliosides aimed at blocking the formation of neurotoxic α-synuclein oligomers in Parkinson's disease
Glycoconjugate Journal - 2021 - Yahi N, Chahinian H, Fantini J.
Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?
The Journal of infection, J Infect. 2021 Aug 9. pii: S0163-4453(21)00392-3. doi: 10.1016/j.jinf.2021.08.010. - 2021 - Fantini J.
Therapeutic and Vaccine Strategies for Stopping the COVID-19 Pandemic Based on Structural and Molecular Modeling Studies of Virus-Ganglioside Interactions
(eBook chapter) In Silico Modeling of Drugs Against Coronaviruses, DOI https://doi.org/10.1007/7653_2020_54 : 273-290 - 2021 - Incontro S, Sammari M, Azzaz F, Inglebert Y, Ankri N, Russier M, Fantini J, Debanne D.
Endocannabinoids tune intrinsic excitability in O-LM interneurons by direct modulation of post-synaptic Kv7 channels
Journal of Neuroscience, 41 : 9521-9538 - 2021 - Assou EL-Battari, Léa Rodriguez, Chahinian H, Olivier Delézay, Fantini J, Yahi N, Coralie Di Scala.
Gene Therapy Strategy for Alzheimer's and Parkinson's Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells
- 2021 - Ramirez-Franco JJ, Azzaz F, Sangiardi M, Ferracci Géraldine, Youssouf F, Popoff Michel Robert, Seagar M, Lévêque C, Fantini JEl Far O.
The protein-binding pocket of Botulinum neurotoxin B accommodates a preassembled synaptotagmin / ganglioside complex
BioRxiv - 2020 - Fantini J, Di Scala C, Chahinian H, Yahi N.
Structural and molecular modeling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
International Journal of Antimicrobial Agents, 55 : 105960 - 2020 - Fantini J, Chahinian H, Yahi N.
Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal
International Journal Antimicrobial Agents, 56 : 106020 - 2020 - Fantini J, Chahinian H, Yahi N.
Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?
Protein Science, 29 : 1748-1759 - 2020 - Fantini J, Chahinian H, Yahi N.
Leveraging coronavirus binding to gangliosides for innovative vaccine and therapeutic strategies against COVID-19
Biochemical and Biophysical Research Communications, doi: 10.1016/j.bbrc.2020.10.015. - 2019 - Flores A, Ramirez-Franco JJ, Desplantes R, Debreux K, Ferracci G, Wernert F, Blanchard MP, Maulet Y, Youssouf FSangiardi M, Iborra C, Popoff MR, Seagar M, Fantini J, Lévêque CEl Far O.
Gangliosides interact with synaptotagmin to form the high-affinity receptor complex for botulinum neurotoxin B
PNAS, www.pnas.org/cgi/doi/10.1073/pnas.1908051116 - 2018 - Coralie Di Scala, Fantini J, Yahi N, Francisco J. Barrantes, Chahinian H.
Anandamide Revisited: How Cholesterol and Ceramides Control Receptor-Dependent and Receptor-Independent Signal Transmission Pathways of a Lipid Neurotransmitter
Biomolecules, 8 - 2018 - Huang Y, Huang S, Di Scala C, Wang Q, Wandall HH, Fantini J, Zhang YQ.
The glycosphingolipid MacCer promotes synaptic bouton2 formation in Drosophila by interacting with Wnt
eLife, 7 : e38183
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